We're here to help you stay informed, connected, and supported during treatment

Recordati Access, Resource, and Engagement (R.A.R.E.) is a patient support program designed to make it easier for you to access and stay on your treatment.

Your enrollment in R.A.R.E. will be processed along with your prescription.

Savings

R.A.R.E. can help eligible commercially-insured patients get their medication for no more than $20 per month*

Your copayment covers your total dosage of ISTURISA, as prescribed by your doctor.

We support you with insurance coverage and access support

An insurance specialist will verify your benefits and support your doctor in obtaining a prior authorization from your insurance provider. They can help you receive the most value from your insurance coverage.

Uninsured? We’re here for you.

Patients who lack insurance and meet certain financial requirements may be eligible for additional financial support from a Patient Assistance Program.*

*Restrictions, limitations, and/or eligibility requirements apply.

I was worried about paying for my ISTURISA treatment, but R.A.R.E. was there to help.

Model shown is not an actual patient.

Support

Your R.A.R.E. Support Team Is Here For You Right From the Start

Our knowledgeable and reliable professionals have been fully trained about ISTURISA, and are dedicated to supporting your treatment goals.

Step 1

Your support team: An Insurance Specialist

An INSURANCE SPECIALIST helps get you the best coverage for your medication

After your doctor has determined ISTURISA is right for you, a R.A.R.E. Insurance Specialist will support you and your doctor’s office in verifying and obtaining insurance coverage.

Step 2

Your support team: 24-7 Pharmacist

PHARMACISTS are available to you 24/7, every day of the year

Once your prescription has been processed, a pharmacist will call you to schedule delivery of your medication to your home or another convenient location, and answer any questions you might have about getting started with treatment. A pharmacist is available over the phone 24/7.

Step 3

Your Support Team: A Nurse Ambassador

A NURSE AMBASSADOR will answer your questions and support you during treatment

Shortly after beginning treatment, a specially trained R.A.R.E. Nurse Ambassador will call you to ensure your treatment is off to a good start, answer questions about your condition or medication, and discuss your treatment goals. You can also look forward to regular phone calls from your R.A.R.E. Nurse Ambassador.

Step 4

The specialty pharmacy ensures you have the refills of the 1, 5, or 10mg tablets of ISTURISA that you may need.

WORRY-FREE Refill Processing helps you stay on track with your treatment

Throughout treatment, the specialty pharmacy will remain in contact with you regarding medication refills and deliveries.

I used to feel alone with my Cushing’s disease—but my Nurse Ambassador understands what I’m going through and helps me with my treatment goals.

You can contact The R.A.R.E. Patient Support Program at: 1-888-855-RARE (7273)

Monday-Friday between 9:00 AM and 6:00 PM ET

A clinical pharmacist is always available to help you—24 hours a day, 7 days a week.

Learn more about the R.A.R.E Patient Support Program.

Download the R.A.R.E Brochure

ISTURISA® (osilodrostat) Important Safety Information

Indications and Usage

ISTURISA (osilodrostat) is used to treat adults with Cushing’s disease who cannot have pituitary surgery, or who have had pituitary surgery, but the surgery did not cure their Cushing’s disease.

Important Safety Information:

  • Hypocortisolism: Treatment with ISTURISA may cause symptoms associated with low levels of cortisol in your blood (hypocortisolism). Tell your healthcare provider right away if you experience more than one of the following symptoms, as these may be symptoms of very low cortisol level, known as adrenal insufficiency: nausea, vomiting, tiredness (fatigue), low blood pressure, stomach (abdominal) pain, loss of appetite, dizziness. If you get symptoms of hypocortisolism while taking ISTURISA, your healthcare provider may change your dose or ask you to stop taking it.

ISTURISA® (osilodrostat) Important Safety Information

Indications and Usage

ISTURISA (osilodrostat) is used to treat adults with Cushing’s disease who cannot have pituitary surgery, or who have had pituitary surgery, but the surgery did not cure their Cushing’s disease.

Important Safety Information:

  • Hypocortisolism: Treatment with ISTURISA may cause symptoms associated with low levels of cortisol in your blood (hypocortisolism). Tell your healthcare provider right away if you experience more than one of the following symptoms, as these may be symptoms of very low cortisol level, known as adrenal insufficiency: nausea, vomiting, tiredness (fatigue), low blood pressure, stomach (abdominal) pain, loss of appetite, dizziness. If you get symptoms of hypocortisolism while taking ISTURISA, your healthcare provider may change your dose or ask you to stop taking it.
  • Heart Problem or Heart Rhythm Problem: ISTURISA may cause an irregular heartbeat which could be a sign of a heart problem called QT prolongation. Call your healthcare provider right away if you have irregular heartbeats.
  • Increase in Other Adrenal Hormone Levels: Your other adrenal hormones may increase when you take ISTURISA. Your healthcare provider may monitor you for the symptoms associated with these hormonal changes while you are taking ISTURISA such as low potassium (hypokalemia), high blood pressure (hypertension), swelling (edema) in the legs, ankles, or other signs of fluid retention, excessive facial or body hair growth (hirsutism), acne (in women). Call your healthcare provider if you have any of these side effects.
  • Most common side effects include very low cortisol levels (adrenal insufficiency), tiredness (fatigue), nausea, headache, swelling of the legs, ankles or other signs of fluid retention (edema). These are not all of the possible side effects of ISTURISA.

To report SUSPECTED SIDE EFFECTS, contact Recordati Rare Diseases Inc. at 1-888-575-8344, or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Before taking ISTURISA, tell your doctor about all of your medical conditions, including if you:

  • have or had heart problems, such as an irregular heartbeat, including a condition called prolonged QT syndrome (QT internal prolongation). Your healthcare provider will check the electrical signal of your heart (called an electrocardiogram) before you start taking ISTURISA, 1 week after starting ISTURISA, and as needed after that.
  • have a history of low levels of potassium or magnesium in your blood.
  • have liver problems.
  • are breastfeeding or plan to breastfeed. It is not known if ISTURISA passes into your breast milk. You should not breastfeed if you take ISTURISA and for 1 week after stopping treatment.

Tell your healthcare provider about all the medicines you take, including prescription medicines, over-the-counter medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take medicines used to treat certain heart problems. Ask your healthcare provider if you are not sure whether your medicine is used to treat heart problems.

Please see the accompanying Full Prescribing Information, including the Medication Guide, for ISTURISA and talk with your healthcare provider.